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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10711
Species: Mus musculus
RGD Object: Gene
Symbol: Hmgb1
Name: high mobility group box 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmgb1affects expressionISOHMGB1 (Homo sapiens)6480464CTDbisphenol A affects the expression of HMGB1 mRNAPMID:30903817
Hmgb1affects expressionISOHmgb1 (Rattus norvegicus)6480464CTDbisphenol A affects the expression of HMGB1 mRNAPMID:25181051
Hmgb1decreases expressionISOHMGB1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of HMGB1 mRNAPMID:29275510
Hmgb1increases expressionISOHMGB1 (Homo sapiens)6480464CTDbisphenol A results in increased expression of HMGB1 proteinPMID:34186270
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