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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10463
Species: Mus musculus
RGD Object: Gene
Symbol: Dbi
Name: diazepam binding inhibitor
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Dbidecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of DBI mRNAPMID:32926169
Dbiincreases expressionEXP 6480464CTDbisphenol A results in increased expression of DBI mRNAPMID:33221593 PMID:37105096
Dbiincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of DBI promoterPMID:27312807
Dbiaffects expressionISODbi (Rattus norvegicus)6480464CTDbisphenol A affects the expression of DBI mRNAPMID:30903817 PMID:32145629
Dbiaffects expressionISODBI (Homo sapiens)6480464CTDbisphenol A affects the expression of DBI mRNAPMID:30903817
Dbidecreases expressionISODbi (Rattus norvegicus)6480464CTDbisphenol A results in decreased expression of DBI mRNA; bisphenol A results in decreased expression of DBI proteinPMID:25181051 PMID:32145629
Dbiincreases expressionISODBI (Homo sapiens)6480464CTDbisphenol A results in increased expression of DBI proteinPMID:37567409
Dbiincreases methylationISODbi (Rattus norvegicus)6480464CTDbisphenol A results in increased methylation of DBI genePMID:28505145
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