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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10216
Species: Homo sapiens
RGD Object: Gene
Symbol: ATP7A
Name: ATPase copper transporting alpha
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
ATP7Aincreases expressionEXP 6480464CTDbisphenol A results in increased expression of ATP7A mRNAPMID:29275510
ATP7Aaffects expressionISOAtp7a (Rattus norvegicus)6480464CTDbisphenol A affects the expression of ATP7A mRNAPMID:25181051
ATP7Adecreases expressionISOAtp7a (Mus musculus)6480464CTDbisphenol A results in decreased expression of ATP7A mRNA; bisphenol A results in decreased expression of ATP7A proteinPMID:27690074
ATP7Aincreases expressionISOAtp7a (Rattus norvegicus)6480464CTDbisphenol A results in increased expression of ATP7A mRNAPMID:30816183 PMID:34947998
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