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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11275
Species: Mus musculus
RGD Object: Gene
Symbol: Ccl2
Name: C-C motif chemokine ligand 2
Acc ID: CHEBI:3312
Term: calcium dichloride
Definition: A calcium salt that has formula CaCl2.
Chemical ID: MESH:D002122
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl2increases expressionEXP 6480464CTDCalcium Chloride results in increased expression of CCL2 mRNA; Calcium Chloride results in increased expression of CCL2 proteinPMID:21530968 PMID:22728078
Ccl2increases phosphorylationEXP 6480464CTDCalcium Chloride results in increased phosphorylation of CCL2 proteinPMID:21530968
Ccl2multiple interactionsEXP 6480464CTDQuercetin inhibits the reaction [Calcium Chloride results in increased expression of CCL2 protein]; resveratrol inhibits the reaction [Calcium Chloride results in increased expression of CCL2 mRNA]; resveratrol inhibits the reaction [Calcium Chloride results in increased phosphorylation of CCL2 protein]PMID:21530968 PMID:22728078
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