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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70373
Species: Homo sapiens
RGD Object: Gene
Symbol: BAX
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:33101
Term: nitrogen dioxide
Definition: A nitrogen oxide that has formula NO2.
Chemical ID: MESH:D009585
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BAXincreases expressionISOBax (Rattus norvegicus)6480464CTDNitrogen Dioxide results in increased expression of BAX mRNA; Nitrogen Dioxide results in increased expression of BAX proteinPMID:22621880
BAXmultiple interactionsISOBax (Mus musculus)6480464CTD[Particulate Matter co-treated with Sulfur Dioxide co-treated with Nitrogen Dioxide] results in increased expression of BAX proteinPMID:27521637
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