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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70970
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hmgcs1
Name: 3-hydroxy-3-methylglutaryl-CoA synthase 1
Acc ID: CHEBI:33083
Term: fluoranthene
Definition: An ortho- and peri-fused polycyclic arene consisting of a naphthalene and benzene unit connected by a five-membered ring.
Chemical ID: MESH:C007738
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hmgcs1decreases expressionISOHmgcs1 (Mus musculus)6480464CTDfluoranthene results in decreased expression of HMGCS1 mRNAPMID:28329830
Hmgcs1multiple interactionsISOHmgcs1 (Mus musculus)6480464CTD[1-methylanthracene co-treated with fluoranthene] results in decreased expression of HMGCS1 mRNAPMID:28329830
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