GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccl5 | multiple interactions | ISO | CCL5 (Homo sapiens) | 6480464 | CTD | CCL5 protein promotes the reaction [Calcimycin affects the abundance of and affects the chemical synthesis of Reactive Oxygen Species]; IL5 protein promotes the reaction [CCL5 protein promotes the reaction [Calcimycin affects the abundance of and affects the chemical synthesis of Reactive Oxygen Species]] | PMID:12797483 | Ccl5 | multiple interactions | ISO | Ccl5 (Rattus norvegicus) | 6480464 | CTD | [Calcimycin co-treated with CCL5 protein] results in increased secretion of Leukotriene B4; CCL5 protein promotes the reaction [Calcimycin results in increased expression of ALOX5 mRNA]; CCL5 protein promotes the reaction [Calcimycin results in increased expression of ALOX5 protein]; Dexamethasone inhibits the reaction [[Calcimycin co-treated with CCL5 protein] results in increased secretion of Leukotriene B4]; Dexamethasone inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 protein]; Masoprocol inhibits the reaction [[Calcimycin co-treated with CCL5 protein] results in increased secretion of Leukotriene B4]; Masoprocol inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 mRNA]; Masoprocol inhibits the reaction [[CCL5 protein co-treated with Calcimycin] results in increased expression of ALOX5 protein] | PMID:18083043 | | ||||||||||||||||||||||
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