Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730951
Species: Homo sapiens
RGD Object: Gene
Symbol: NOS2
Name: nitric oxide synthase 2
Acc ID: CHEBI:33007
Term: chromium(6+)
Definition: A monoatomic hexacation that has formula Cr.
Chemical ID: MESH:C074702
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NOS2increases expressionEXP 6480464CTDchromium hexavalent ion results in increased expression of NOS2 mRNA; chromium hexavalent ion results in increased expression of NOS2 proteinPMID:25448439
NOS2multiple interactionsEXP 6480464CTDLuteolin inhibits the reaction [chromium hexavalent ion results in increased expression of NOS2 mRNA]; Luteolin inhibits the reaction [chromium hexavalent ion results in increased expression of NOS2 protein]PMID:25448439
NOS2multiple interactionsISONos2 (Rattus norvegicus)6480464CTD[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of NOS2 protein; S-allylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of NOS2 protein]PMID:28988497
Go Back to source page   Continue to Ontology report