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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621543
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Chek2
Name: checkpoint kinase 2
Acc ID: CHEBI:33007
Term: chromium(6+)
Definition: A monoatomic hexacation that has formula Cr.
Chemical ID: MESH:C074702
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Chek2increases phosphorylationISOCHEK2 (Homo sapiens)6480464CTDchromium hexavalent ion results in increased phosphorylation of CHEK2 proteinPMID:31388677
Chek2multiple interactionsISOCHEK2 (Homo sapiens)6480464CTDAscorbic Acid inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of CHEK2 protein]PMID:31388677
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