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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620944
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp7
Name: caspase 7
Acc ID: CHEBI:33007
Term: chromium(6+)
Definition: A monoatomic hexacation that has formula Cr.
Chemical ID: MESH:C074702
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp7affects expressionISOCasp7 (Mus musculus)6480464CTDchromium hexavalent ion affects the expression of CASP7 mRNAPMID:28472532
Casp7increases activityISOCASP7 (Homo sapiens)6480464CTDchromium hexavalent ion results in increased activity of CASP7 proteinPMID:15831465
Casp7increases cleavageISOCASP7 (Homo sapiens)6480464CTDchromium hexavalent ion results in increased cleavage of CASP7 proteinPMID:17301063
Casp7multiple interactionsISOCASP7 (Homo sapiens)6480464CTDAscorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of CASP7 protein]; MLH1 protein affects the reaction [chromium hexavalent ion results in increased activity of CASP7 protein]PMID:15831465 PMID:17301063
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