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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2460
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp1b1
Name: cytochrome P450, family 1, subfamily b, polypeptide 1
Acc ID: CHEBI:33007
Term: chromium(6+)
Definition: A monoatomic hexacation that has formula Cr.
Chemical ID: MESH:C074702
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1b1decreases expressionISOCYP1B1 (Homo sapiens)6480464CTDchromium hexavalent ion results in decreased expression of CYP1B1 mRNAPMID:30690063
Cyp1b1multiple interactionsISOCyp1b1 (Mus musculus)6480464CTD[chromium hexavalent ion co-treated with Benzo(a)pyrene] affects the expression of CYP1B1 mRNAPMID:25820237
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