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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316317
Species: Mus musculus
RGD Object: Gene
Symbol: Bub1b
Name: BUB1B, mitotic checkpoint serine/threonine kinase
Acc ID: CHEBI:33007
Term: chromium(6+)
Definition: A monoatomic hexacation that has formula Cr.
Chemical ID: MESH:C074702
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bub1bdecreases expressionISOBUB1B (Homo sapiens)6480464CTDchromium hexavalent ion results in decreased expression of BUB1B proteinPMID:22886373
Bub1bmultiple interactionsISOBUB1B (Homo sapiens)6480464CTDpifithrin inhibits the reaction [TP53 protein promotes the reaction [chromium hexavalent ion results in decreased expression of BUB1B protein]]; TP53 protein promotes the reaction [chromium hexavalent ion results in decreased expression of BUB1B protein]PMID:22886373
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