Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	1313299
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	MDM2
Name:	MDM2 proto-oncogene

Acc ID:	CHEBI:32687
Term:	piperonyl butoxide
Definition:	A benzodioxole that has formula C19H30O5.
Chemical ID:	MESH:D010882

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
MDM2	increases expression	ISO	Mdm2 (Rattus norvegicus)	6480464	CTD	Piperonyl Butoxide results in increased expression of MDM2 mRNA	PMID:15890375 PMID:22484513

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.