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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736867
Species: Mus musculus
RGD Object: Gene
Symbol: Abcc3
Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 3
Acc ID: CHEBI:32636
Term: acetaminophen O-beta-D-glucosiduronic acid
Definition: A beta-D-glucosiduronic acid that is the O-glucuronide of paracetamol (acetaminophen).
Chemical ID: MESH:C037386
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc3affects exportEXP 6480464CTDABCC3 protein affects the export of acetaminophen glucuronide

PMID:16250050
Abcc3increases activityISORGD:7368666480464CTDacetaminophen glucuronide results in increased activity of ABCC3 protein

PMID:17569508
Abcc3multiple interactionsISORGD:711016480464CTDEthinyl Estradiol promotes the reaction [ABCC3 protein results in increased secretion of acetaminophen glucuronide]

PMID:16554369
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