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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10274
Species: Mus musculus
RGD Object: Gene
Symbol: Calca
Name: calcitonin/calcitonin-related polypeptide, alpha
Acc ID: CHEBI:32588
Term: potassium chloride
Definition: A metal chloride salt with a K(+) counterion.
Chemical ID: MESH:D011189
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Calcaincreases expressionISOCalca (Rattus norvegicus)6480464CTDPotassium Chloride results in increased expression of CALCA mRNAPMID:12574409
Calcaincreases secretionISOCalca (Rattus norvegicus)6480464CTDPotassium Chloride results in increased secretion of CALCA proteinPMID:14991081 PMID:16942474 PMID:17640294 PMID:17997062 PMID:18052948 PMID:19096234 PMID:27030709
Calcamultiple interactionsISOCalca (Rattus norvegicus)6480464CTDCarbon Dioxide inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]; Enkephalin, Ala(2)-MePhe(4)-Gly(5)- inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]; Fentanyl inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]; Naloxone inhibits the reaction [Enkephalin, Ala(2)-MePhe(4)-Gly(5)- inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]]; Naloxone inhibits the reaction [Fentanyl inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]]; Nefopam inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]; nociceptin (1-13) amide inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]; Plant Extracts inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]; Polyphenols inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]; topiramate inhibits the reaction [Potassium Chloride results in increased secretion of CALCA protein]PMID:16942474 PMID:17640294 PMID:17997062 PMID:18052948 PMID:19096234 PMID:27030709
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