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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306715
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rev1
Name: REV1, DNA directed polymerase
Acc ID: CHEBI:32585
Term: 4-hydroxynon-2-enal
Definition: An enal consisting of non-2-ene having an oxo group at the 1-position and a hydroxy group at the 4-position.
Chemical ID: MESH:C027576
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects response to substanceISORGD:13154926480464CTDREV1 protein affects the susceptibility to 4-hydroxy-2-nonenal

PMID:22331492
multiple interactionsISORGD:13154926480464CTDREV1 protein affects the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of H2AX protein]

PMID:22331492
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