Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735868
Species: Homo sapiens
RGD Object: Gene
Symbol: NQO1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
affects expressionISORGD:104736480464CTDpirinixic acid affects the expression of NQO1 mRNA

PMID:19136022
decreases expressionISORGD:25036480464CTDpirinixic acid results in decreased expression of NQO1 mRNA

PMID:19162173
increases expressionISORGD:104736480464CTDpirinixic acid results in increased expression of NQO1 mRNA

PMID:17950772, PMID:18301758, PMID:20059764, PMID:20813756, PMID:23811191
increases expressionISORGD:25036480464CTDpirinixic acid results in increased expression of NQO1 mRNA

PMID:15890375
multiple interactionsISORGD:104736480464CTDPPARA protein promotes the reaction [pirinixic acid results in increased expression of NQO1 mRNA]

PMID:17950772, PMID:20059764
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.