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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732204
Species: Homo sapiens
RGD Object: Gene
Symbol: CSAD
Name: cysteine sulfinic acid decarboxylase
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CSADdecreases expressionISOCsad (Mus musculus)6480464CTDpirinixic acid results in decreased expression of CSAD mRNA; pirinixic acid results in decreased expression of CSAD proteinPMID:15226431 PMID:18445702
CSADincreases expressionISOCsad (Rattus norvegicus)6480464CTDpirinixic acid results in increased expression of CSAD mRNAPMID:19162173
CSADincreases expressionISOCsad (Mus musculus)6480464CTDpirinixic acid results in increased expression of CSAD mRNAPMID:17426115 PMID:18301758 PMID:23811191
CSADmultiple interactionsISOCsad (Mus musculus)6480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of CSAD mRNAPMID:19710929
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