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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69244
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcd2
Name: ATP binding cassette subfamily D member 2
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcd2affects expressionISOAbcd2 (Mus musculus)6480464CTDpirinixic acid affects the expression of ABCD2 mRNAPMID:19136022
Abcd2increases expressionISOAbcd2 (Mus musculus)6480464CTDpirinixic acid results in increased expression of ABCD2 mRNAPMID:15302862 PMID:15375163 PMID:18301758 PMID:20059764 PMID:20813756
Abcd2multiple interactionsISOABCD2 (Homo sapiens)6480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ABCD2 mRNAPMID:19710929
Abcd2multiple interactionsISOAbcd2 (Mus musculus)6480464CTDPPARA protein promotes the reaction [pirinixic acid results in increased expression of ABCD2 mRNA]PMID:20059764
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