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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620600
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nox4
Name: NADPH oxidase 4
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nox4decreases expressionEXP 6480464CTDpirinixic acid results in decreased expression of NOX4 mRNAPMID:19162173
Nox4decreases expressionISONox4 (Mus musculus)6480464CTDpirinixic acid results in decreased expression of NOX4 mRNAPMID:20813756
Nox4multiple interactionsISONox4 (Mus musculus)6480464CTD[pirinixic acid co-treated with PPARA] results in decreased expression of NOX4 mRNAPMID:20813756
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