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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2719
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gnmt
Name: glycine N-methyltransferase
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gnmtdecreases expressionEXP 6480464CTDpirinixic acid results in decreased expression of GNMT mRNAPMID:17164430 PMID:19162173
Gnmtdecreases expressionISOGnmt (Mus musculus)6480464CTDpirinixic acid results in decreased expression of GNMT mRNA; pirinixic acid results in decreased expression of GNMT proteinPMID:15226431 PMID:16221962 PMID:20813756
Gnmtdecreases expressionISOGNMT (Homo sapiens)6480464CTDpirinixic acid results in decreased expression of GNMT mRNAPMID:35690182
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