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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2476
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2f4
Name: cytochrome P450, family 2, subfamily f, polypeptide 4
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2f4affects expressionEXP 6480464CTDpirinixic acid affects the expression of CYP2F4 mRNAPMID:19483382
Cyp2f4decreases expressionEXP 6480464CTDpirinixic acid results in decreased expression of CYP2F4 mRNAPMID:19162173 PMID:22484513
Cyp2f4decreases expressionISOCyp2f2 (Mus musculus)6480464CTDpirinixic acid results in decreased expression of CYP2F2 mRNAPMID:15302862 PMID:15375163 PMID:20813756
Cyp2f4multiple interactionsISOCyp2f2 (Mus musculus)6480464CTD[pirinixic acid co-treated with PPARA] results in decreased expression of CYP2F2 mRNAPMID:20813756
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