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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2007
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcd3
Name: ATP binding cassette subfamily D member 3
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcd3increases expressionISOAbcd3 (Mus musculus)6480464CTDpirinixic acid results in increased expression of ABCD3 mRNA; pirinixic acid results in increased expression of ABCD3 proteinPMID:15375163 PMID:17118139 PMID:17426115 PMID:17690133 PMID:18301758 PMID:18593727 PMID:20059764 PMID:20813756 PMID:23811191
Abcd3multiple interactionsISOAbcd3 (Mus musculus)6480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ABCD3 mRNA; PPARA protein promotes the reaction [pirinixic acid results in increased expression of ABCD3 mRNA]PMID:18489776 PMID:20059764
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