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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1594556
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tnfaip2
Name: TNF alpha induced protein 2
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:13122356480464CTDpirinixic acid results in decreased expression of TNFAIP2 mRNA

PMID:18445702
multiple interactionsISORGD:13122356480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of TNFAIP2 mRNA

PMID:19710929
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.