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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319195
Species: Mus musculus
RGD Object: Gene
Symbol: Stat6
Name: signal transducer and activator of transcription 6
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Stat6decreases expressionEXP 6480464CTDpirinixic acid results in decreased expression of STAT6 mRNAPMID:18445702 PMID:20059764
Stat6multiple interactionsEXP 6480464CTDPPARA protein promotes the reaction [pirinixic acid results in decreased expression of STAT6 mRNA]PMID:20059764
Stat6multiple interactionsISOSTAT6 (Homo sapiens)6480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of STAT6 mRNAPMID:19710929
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