Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1316856
Species: Homo sapiens
RGD Object: Gene
Symbol: FBXO4
Name: F-box protein 4
Acc ID: CHEBI:32509
Term: pirinixic acid
Definition: An aryl sulfide that has formula C14H14ClN3O2S.
Chemical ID: MESH:C006253
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
FBXO4increases expressionISORGD:13168576480464CTDpirinixic acid results in increased expression of FBXO4 mRNA

PMID:21318169
FBXO4multiple interactionsISORGD:13168576480464CTD[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of FBXO4 mRNA, PPARA protein affects the reaction [pirinixic acid results in increased expression of FBXO4 mRNA]

PMID:19710929, PMID:21318169
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.