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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735707
Species: Homo sapiens
RGD Object: Gene
Symbol: IL1A
Name: interleukin 1 alpha
Acc ID: CHEBI:32497
Term: thioacetamide
Definition: A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.
Chemical ID: MESH:D013853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1Aincreases expressionISOIl1a (Mus musculus)6480464CTDThioacetamide results in increased expression of IL1A mRNAPMID:36343683
IL1Aincreases expressionISOIl1a (Rattus norvegicus)6480464CTDThioacetamide results in increased expression of IL1A mRNA; Thioacetamide results in increased expression of IL1A proteinPMID:25051504 PMID:34492290
IL1Amultiple interactionsISOIl1a (Mus musculus)6480464CTDEdaravone inhibits the reaction [Thioacetamide results in increased expression of IL1A mRNA]PMID:36343683
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