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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621392
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccn2
Name: cellular communication network factor 2
Acc ID: CHEBI:32497
Term: thioacetamide
Definition: A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.
Chemical ID: MESH:D013853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDThioacetamide results in increased expression of CCN2 protein

PMID:22899499
multiple interactionsEXP 6480464CTDCoffee inhibits the reaction [Thioacetamide results in increased expression of CCN2 protein]

PMID:22899499
increases expressionISORGD:7310146480464CTDThioacetamide results in increased expression of CCN2 mRNA

PMID:28560358
multiple interactionsISORGD:7310146480464CTD[Ethanol co-treated with Thioacetamide] results in increased expression of CCN2 mRNA, TGFBR1 protein promotes the reaction [Thioacetamide results in increased expression of CCN2 mRNA]

PMID:21863215, PMID:28560358
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.