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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621317
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp3
Name: matrix metallopeptidase 3
Acc ID: CHEBI:32497
Term: thioacetamide
Definition: A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.
Chemical ID: MESH:D013853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp3increases expressionEXP 6480464CTDThioacetamide results in increased expression of MMP3 mRNAPMID:16489207 PMID:34492290
Mmp3multiple interactionsEXP 6480464CTDhalofuginone promotes the reaction [Thioacetamide results in increased expression of MMP3 mRNA]PMID:16489207
Mmp3multiple interactionsISOMmp3 (Mus musculus)6480464CTD[Ethanol co-treated with Thioacetamide] results in increased expression of MMP3 mRNA; CNR1 gene mutant form inhibits the reaction [[Ethanol co-treated with Thioacetamide] results in increased expression of MMP3 mRNA]PMID:21863215
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