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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620196
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mmp13
Name: matrix metallopeptidase 13
Acc ID: CHEBI:32497
Term: thioacetamide
Definition: A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.
Chemical ID: MESH:D013853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mmp13increases expressionEXP 6480464CTDThioacetamide results in increased expression of MMP13 mRNA; Thioacetamide results in increased expression of MMP13 proteinPMID:16489207 PMID:22899499 PMID:30883860 PMID:34492290
Mmp13multiple interactionsEXP 6480464CTDCoffee inhibits the reaction [Thioacetamide results in increased expression of MMP13 protein]; halofuginone promotes the reaction [Thioacetamide results in increased expression of MMP13 mRNA]; rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of MMP13 protein]PMID:16489207 PMID:22899499 PMID:30883860
Mmp13increases expressionISOMmp13 (Mus musculus)6480464CTDThioacetamide results in increased expression of MMP13 mRNAPMID:18395095
Mmp13multiple interactionsISOMmp13 (Mus musculus)6480464CTDKRT18 protein affects the reaction [Thioacetamide results in increased expression of MMP13 mRNA]PMID:18395095
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