GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Il10 | decreases expression | EXP | | 6480464 | CTD | Thioacetamide results in decreased expression of IL10 protein | PMID:25051504 PMID:37150287 | Il10 | increases expression | EXP | | 6480464 | CTD | Thioacetamide results in increased expression of IL10 mRNA; Thioacetamide results in increased expression of IL10 protein | PMID:22899499 PMID:26957569 PMID:30883860 | Il10 | multiple interactions | EXP | | 6480464 | CTD | [Berberine co-treated with Thioacetamide] results in increased expression of IL10 mRNA; Coffee inhibits the reaction [Thioacetamide results in increased expression of IL10 protein]; indole-3-carbinol inhibits the reaction [Thioacetamide results in decreased expression of IL10 protein]; rebaudioside A inhibits the reaction [Thioacetamide results in increased expression of IL10 protein] | PMID:22899499 PMID:30138605 PMID:30883860 PMID:37150287 | Il10 | multiple interactions | ISO | Il10 (Mus musculus) | 6480464 | CTD | IL10 protein inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA]; IL10 protein inhibits the reaction [Thioacetamide results in increased expression of ICAM1 mRNA]; IL10 protein inhibits the reaction [Thioacetamide results in increased expression of PTGS2 protein]; IL10 protein inhibits the reaction [Thioacetamide results in increased expression of TGFB1 mRNA]; IL10 protein inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]; IL10 protein inhibits the reaction [Thioacetamide results in increased expression of TIMP2 mRNA]; IL10 protein inhibits the reaction [Thioacetamide results in increased expression of TNF mRNA]; IL10 protein inhibits the reaction [Thioacetamide results in increased expression of VCAM1 mRNA] | PMID:16126171 | |
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