GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | TIMP1 | increases expression | ISO | Timp1 (Rattus norvegicus) | 6480464 | CTD | Thioacetamide results in increased expression of TIMP1 mRNA; Thioacetamide results in increased expression of TIMP1 protein | PMID:11925456 PMID:15158331 PMID:15464241 PMID:16489207 PMID:23411599 PMID:23558518 PMID:26957569 PMID:34492290 | TIMP1 | increases expression | ISO | Timp1 (Mus musculus) | 6480464 | CTD | Thioacetamide results in increased expression of TIMP1 mRNA; Thioacetamide results in increased expression of TIMP1 protein | PMID:16126171 PMID:16511523 PMID:18395095 PMID:27363783 PMID:28845018 PMID:31935363 | TIMP1 | multiple interactions | ISO | Timp1 (Rattus norvegicus) | 6480464 | CTD | [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of TIMP1 mRNA; Cysteine inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]; halofuginone inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]; Methionine inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]; Nucleotides inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein]; Thalidomide inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA] | PMID:11925456 PMID:15158331 PMID:15464241 PMID:16489207 PMID:28943392 | TIMP1 | multiple interactions | ISO | Timp1 (Mus musculus) | 6480464 | CTD | 2,5-dimethyl-4-benzoquinone inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]; 2,5-dimethyl-4-benzoquinone inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein]; 2-tert-butyl-4-quinone inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]; 2-tert-butyl-4-quinone inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein]; [Ethanol co-treated with Thioacetamide] results in increased expression of TIMP1 mRNA; [Thioacetamide co-treated with Ethanol] results in increased expression of TIMP1 protein; ACE2 gene mutant form promotes the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]; CNR1 gene mutant form inhibits the reaction [[Ethanol co-treated with Thioacetamide] results in increased expression of TIMP1 mRNA]; cucurbitacin E inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein]; Curcumin inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein]; IL10 protein inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]; KRT18 protein affects the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]; phenylbenzoquinone inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]; phenylbenzoquinone inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein]; POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of and results in increased activity of TIMP1 protein]; POMC protein alternative form inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]; Thioacetamide results in increased expression of and results in increased activity of TIMP1 protein; thymoquinone inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA]; thymoquinone inhibits the reaction [Thioacetamide results in increased expression of TIMP1 protein] | PMID:16126171 PMID:16511523 PMID:16780996 PMID:18395095 PMID:21863215 PMID:27363783 PMID:28845018 PMID:31935363 | | ||||||||||||||||||||||
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