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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344832
Species: Homo sapiens
RGD Object: Gene
Symbol: TNFSF10
Name: TNF superfamily member 10
Acc ID: CHEBI:32497
Term: thioacetamide
Definition: A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.
Chemical ID: MESH:D013853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNFSF10decreases expressionISOTnfsf10 (Rattus norvegicus)6480464CTDThioacetamide results in decreased expression of TNFSF10 mRNAPMID:23411599 PMID:29133031 PMID:34492290
TNFSF10multiple interactionsISOTnfsf10 (Rattus norvegicus)6480464CTD[Diethylnitrosamine co-treated with Thioacetamide co-treated with Thioctic Acid] results in decreased expression of TNFSF10 mRNA; chloroquine diphosphate inhibits the reaction [Thioacetamide results in decreased expression of TNFSF10 mRNA]; chloroquine diphosphate promotes the reaction [Doxorubicin inhibits the reaction [Thioacetamide results in decreased expression of TNFSF10 mRNA]]; Doxorubicin inhibits the reaction [Thioacetamide results in decreased expression of TNFSF10 mRNA]; Doxorubicin promotes the reaction [chloroquine diphosphate inhibits the reaction [Thioacetamide results in decreased expression of TNFSF10 mRNA]]PMID:23830814 PMID:29133031
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