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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1312374
Species: Mus musculus
RGD Object: Gene
Symbol: Lrp6
Name: low density lipoprotein receptor-related protein 6
Acc ID: CHEBI:32497
Term: thioacetamide
Definition: A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.
Chemical ID: MESH:D013853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lrp6increases expressionISOLrp6 (Rattus norvegicus)6480464CTDThioacetamide results in increased expression of LRP6 mRNAPMID:32961231
Lrp6multiple interactionsISOLrp6 (Rattus norvegicus)6480464CTDNiclosamide inhibits the reaction [Thioacetamide results in increased expression of LRP6 mRNA]; Poloxamer promotes the reaction [Niclosamide inhibits the reaction [Thioacetamide results in increased expression of LRP6 mRNA]]PMID:32961231
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