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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11070
Species: Mus musculus
RGD Object: Gene
Symbol: Pdgfrb
Name: platelet derived growth factor receptor, beta polypeptide
Acc ID: CHEBI:32497
Term: thioacetamide
Definition: A thiocarboxamide consiting of acetamide having the oxygen replaced by sulfur.
Chemical ID: MESH:D013853
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pdgfrbincreases expressionISOPdgfrb (Rattus norvegicus)6480464CTDThioacetamide results in increased expression of PDGFRB proteinPMID:15158331 PMID:15288473
Pdgfrbmultiple interactionsISOPdgfrb (Rattus norvegicus)6480464CTDCysteine inhibits the reaction [Thioacetamide results in increased expression of PDGFRB protein]; inchinko-to inhibits the reaction [Thioacetamide results in increased expression of PDGFRB protein]; Iron, Dietary affects the reaction [Thioacetamide affects the expression of PDGFRB mRNA]; Methionine inhibits the reaction [Thioacetamide results in increased expression of PDGFRB protein]PMID:15158331 PMID:15288473 PMID:18032466
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