Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	735779
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	DIO2
Name:	iodothyronine deiodinase 2

Acc ID:	CHEBI:3237
Term:	butein
Definition:	A chalcone that is (E)-chalcone bearing four additional hydroxy substituents at positions 2', 3, 4 and 4'.
Chemical ID:	MESH:C040918

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
DIO2	decreases activity	EXP		6480464	CTD	butein results in decreased activity of DIO2 protein	PMID:17327447

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.