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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Rela
Name: RELA proto-oncogene, NF-kB subunit
Acc ID: CHEBI:32269
Term: tropisetron
Definition: An indolyl carboxylate ester obtained by formal condensation of the carboxy group of indole-3-carboxylic acid with the hydroxy group of tropine.
Chemical ID: MESH:C045504
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Relamultiple interactionsEXP 6480464CTDTropisetron inhibits the reaction [Streptozocin results in increased expression of RELA protein]PMID:36504472
Relamultiple interactionsISORELA (Homo sapiens)6480464CTD[Paclitaxel co-treated with Tropisetron] results in decreased expression of RELA proteinPMID:34654991
Relamultiple interactionsISORela (Mus musculus)6480464CTD[Paclitaxel co-treated with Tropisetron] results in decreased expression of RELA proteinPMID:34654991
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