Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	2275
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Casp3
Name:	caspase 3

Acc ID:	CHEBI:32269
Term:	tropisetron
Definition:	An indolyl carboxylate ester obtained by formal condensation of the carboxy group of indole-3-carboxylic acid with the hydroxy group of tropine.
Chemical ID:	MESH:C045504

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Casp3	increases expression	ISO	RGD:10289	6480464	CTD	Tropisetron results in increased expression of CASP3 protein modified form	PMID:34654991
Casp3	increases expression	ISO	RGD:731002	6480464	CTD	Tropisetron results in increased expression of CASP3 protein modified form	PMID:34654991
Casp3	multiple interactions	ISO	RGD:10289	6480464	CTD	Paclitaxel inhibits the reaction [Tropisetron results in increased expression of CASP3 protein modified form]	PMID:34654991

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