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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731789
Species: Mus musculus
RGD Object: Gene
Symbol: P4ha1
Name: procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
Acc ID: CHEBI:32234
Term: titanium dioxide
Definition: A titanium oxide with the formula TiO2. A naturally occurring oxide sourced from ilmenite, rutile and anatase, it has a wide range of applications.
Chemical ID: MESH:C009495
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
P4ha1increases expressionEXP 6480464CTDtitanium dioxide results in increased expression of P4HA1 mRNAPMID:23131501 PMID:23409001 PMID:31298478
P4ha1multiple interactionsEXP 6480464CTDResveratrol inhibits the reaction [titanium dioxide results in increased expression of P4HA1 mRNA]PMID:31298478
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