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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731383
Species: Mus musculus
RGD Object: Gene
Symbol: Kit
Name: KIT proto-oncogene receptor tyrosine kinase
Acc ID: CHEBI:32234
Term: titanium dioxide
Definition: A titanium oxide with the formula TiO2. A naturally occurring oxide sourced from ilmenite, rutile and anatase, it has a wide range of applications.
Chemical ID: MESH:C009495
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kitaffects expressionEXP 6480464CTDtitanium dioxide affects the expression of KIT mRNAPMID:23557971
Kitmultiple interactionsEXP 6480464CTD[titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of KIT mRNAPMID:29950665
Kitdecreases expressionISOKit (Rattus norvegicus)6480464CTDtitanium dioxide results in decreased expression of KIT mRNAPMID:28844848
Kitmultiple interactionsISOKit (Rattus norvegicus)6480464CTDmorin inhibits the reaction [titanium dioxide results in decreased expression of KIT mRNA]PMID:28844848
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