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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2294
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ccne1
Name: cyclin E1
Acc ID: CHEBI:32234
Term: titanium dioxide
Definition: A titanium oxide with the formula TiO2. A naturally occurring oxide sourced from ilmenite, rutile and anatase, it has a wide range of applications.
Chemical ID: MESH:C009495
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccne1increases expressionEXP 6480464CTDtitanium dioxide results in increased expression of CCNE1 mRNAPMID:30012374
Ccne1increases expressionISOCcne1 (Mus musculus)6480464CTDtitanium dioxide results in increased expression of CCNE1 mRNAPMID:23557971
Ccne1multiple interactionsISOCCNE1 (Homo sapiens)6480464CTD[Vitallium analog binds to titanium dioxide] which results in decreased expression of CCNE1 mRNAPMID:23825117
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