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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1319838
Species: Mus musculus
RGD Object: Gene
Symbol: Polr2b
Name: polymerase (RNA) II (DNA directed) polypeptide B
Acc ID: CHEBI:3223
Term: buspirone
Definition: An azaspiro compound that is 8-azaspiro[4.5]decane-7,9-dione substituted at the nitrogen atom by a 4-(piperazin-1-yl)butyl group which in turn is substituted by a pyrimidin-2-yl group at the N(4) position.
Chemical ID: MESH:D002065
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Polr2bdecreases expressionISOPolr2b (Rattus norvegicus)6480464CTDBuspirone results in decreased expression of POLR2B mRNAPMID:24136188
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