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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69106
Species: Mus musculus
RGD Object: Gene
Symbol: Nr1i2
Name: nuclear receptor subfamily 1, group I, member 2
Acc ID: CHEBI:32221
Term: tiaprofenic acid
Definition: An aromatic ketone that is thiophene substituted at C-2 by benzoyl and at C-4 by a 1-carboxyethyl group.
Chemical ID: MESH:C021270
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1i2increases activityISONR1I2 (Homo sapiens)6480464CTDtiaprofenic acid results in increased activity of NR1I2 proteinPMID:25455453
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