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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 730833
Species: Homo sapiens
RGD Object: Gene
Symbol: SOCS3
Name: suppressor of cytokine signaling 3
Acc ID: CHEBI:32168
Term: sulpiride
Definition: A member of the class of benzamides obtained from formal condensation between the carboxy group of 2-methoxy-5-sulfamoylbenzoic acid and the primary amino group of (1-ethylpyrrolidin-2-yl)methylamine.
Chemical ID: MESH:D013469
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
SOCS3increases expressionISOSocs3 (Rattus norvegicus)6480464CTDSulpiride results in increased expression of SOCS3 mRNAPMID:18162529
SOCS3multiple interactionsISOSocs3 (Rattus norvegicus)6480464CTDEstradiol promotes the reaction [Sulpiride results in increased expression of SOCS3 mRNA]PMID:18162529
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