GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Drd2 | affects binding | EXP | | 6480464 | CTD | Sulpiride binds to DRD2 protein | PMID:2901473 | Drd2 | decreases activity | EXP | | 6480464 | CTD | Sulpiride results in decreased activity of DRD2 protein | PMID:7644023 | Drd2 | increases expression | EXP | | 6480464 | CTD | Sulpiride results in increased expression of DRD2 | PMID:1351265 | Drd2 | multiple interactions | EXP | | 6480464 | CTD | Methamphetamine inhibits the reaction [Sulpiride binds to DRD2 protein]; Sulpiride binds to and results in decreased activity of DRD2 protein; Sulpiride inhibits the reaction [Tacrolimus affects the activity of DRD2 protein] | PMID:15332494 PMID:2891082 PMID:8774428 | Drd2 | affects binding | ISO | DRD2 (Homo sapiens) | 6480464 | CTD | Sulpiride binds to DRD2 protein | PMID:20361897 | Drd2 | multiple interactions | ISO | Drd2 (Mus musculus) | 6480464 | CTD | [Sulpiride binds to and results in decreased activity of DRD2 protein] which results in decreased susceptibility to Methamphetamine | PMID:20340177 | Drd2 | multiple interactions | ISO | DRD2 (Homo sapiens) | 6480464 | CTD | Sulpiride inhibits the reaction [[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium]; Sulpiride inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium] | PMID:8032591 | |
Go Back to source page | Continue to Ontology report |