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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732433
Species: Mus musculus
RGD Object: Gene
Symbol: Itgam
Name: integrin alpha M
Acc ID: CHEBI:3215
Term: bupivacaine
Definition: A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
Chemical ID: MESH:D002045
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itgamincreases expressionEXP 6480464CTDBupivacaine results in increased expression of ITGAM mRNAPMID:19359520
Itgammultiple interactionsEXP 6480464CTD4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine inhibits the reaction [Bupivacaine results in increased expression of ITGAM mRNA]PMID:19359520
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