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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3673
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Shh
Name: sonic hedgehog signaling molecule
Acc ID: CHEBI:32111
Term: saccharin
Definition: A 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent.
Chemical ID: MESH:D012439
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Shhdecreases expressionISORGD:7368306480464CTDSaccharin results in decreased expression of SHH mRNA

PMID:26272751
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