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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1346464
Species: Homo sapiens
RGD Object: Gene
Symbol: H2AX
Name: H2A.X variant histone
Acc ID: CHEBI:32063
Term: propylparaben
Definition: The benzoate ester that is the propyl ester of 4-hydroxybenzoic acid. Preservative typically found in many water-based cosmetics, such as creams, lotions, shampoos and bath products. Also used as a food additive.
Chemical ID: MESH:C006068
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
H2AXincreases expressionEXP 6480464CTDpropylparaben results in increased expression of H2AX protein modified formPMID:31939680
H2AXmultiple interactionsEXP 6480464CTDFulvestrant inhibits the reaction [propylparaben results in increased expression of H2AX protein modified form]PMID:31939680
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