Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	10652
Species:	Mus musculus
RGD Object:	Gene
Symbol:	Gclc
Name:	glutamate-cysteine ligase, catalytic subunit

Acc ID:	CHEBI:3197
Term:	Brusatol
Definition:	A triterpenoid that has formula C26H32O11.
Chemical ID:	MESH:C020237

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Gclc	decreases expression	ISO	GCLC (Homo sapiens)	6480464	CTD	brusatol results in decreased expression of GCLC protein	PMID:27639429

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.