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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70913
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc5
Name: ATP binding cassette subfamily C member 5
Acc ID: CHEBI:31941
Term: oxaliplatin
Definition: A platinum coordination entity that is a commonly used chemothrepeutic drug for treatment of colorectal cancer.
Chemical ID: MESH:C030110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc5affects response to substanceISOABCC5 (Homo sapiens)6480464CTDABCC5 protein affects the susceptibility to oxaliplatinPMID:24924344
Abcc5decreases response to substanceISOABCC5 (Homo sapiens)6480464CTDABCC5 protein results in decreased susceptibility to oxaliplatinPMID:15897250
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